AML-riktlinjer 20120522 - svenska aml-gruppen

Epidemiological studies in de novo and secondary acute leukemia

Acute lymphoblastic leukemia (ALL) accounts for the greatest number of  Short leukocyte telomeres, but not telomere attrition rates, predict memory decline in the 20-year longitudinal Betula study. The journals of gerontology. Series A  Treatment of AML and ALL 21. Intentions of treatment and strategy 21.

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While lymphoblastic lymphomas represent a small percentage of non-Hodgkin lymphomas overall, the majority of cases are T-LBL. Optimal treatment for T-LBL has not yet been established and predictive biological 2006-03-02 Seventeen patients (58.6%) presented with peripheral lymphadenopathy and 13 of them (44.8%) had involvement of bone marrow or peripheral blood. Mediastinal involvement was found only in 5 cases (17.2%). Twenty-one patients (72.4%) were in stage III or IV at diagnosis. The 1-year and 5-year survival rates were 53.3% and 36.7%, respectively. Treatment approaches in T-LBL changed from conventional non-Hodgkin lymphoma (NHL) protocols to intensive NHL protocols but recently to ALL-designed protocols. T-ALL remission rates are 90%, and overall survival (OS) has improved to 60%-70%.

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In this study, we assessed the safety and efficacy of tandem autologous hematopoietic stem cell transplantation (auto-HSCT) strategy for adult T-LBL and evaluated prognostic factors affecting survival. 181 Newly-diagnosed adult T-LBL patients were 2006-08-31 · The overall survival (OS) rate was 55.1% at 1 year, 31.5% at 5 years, and 23.6% at 9 years. The disease-free survival (DFS) rate was 46.7% at 1 year and 30.0% at 7 years.

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The average five-year survival in ALL is 68.1%. Survival rates continue to improve with newer and improved treatment modalities.

Among all histological type subgroups, the prognosis of NK/T-cell lymphoma was the worst with the 3-year survival rate of only 25%u the 3-year survival rate was 40% in unspecified peripheral T-cell lymphoma group,and 85% in angioimmunoblast T-cell lymphoma group. Introduction Despite improvements in the prognosis of acute lymphoblastic leukemia (ALL), it is still the most common childhood cancer. The goal of this study was to investigate if there was a significant difference in the five-year survival between Black and White children with ALL, specifically up to the year 2016 which has not been researched. The Stanford/NCOG regimen is an effective initial choice of therapy for lymphoblastic lymphoma patients, and is superior to the hyper-CVAD regimen in complete response rate and overall survival rate … In the 1950s, the rate of survival for pediatric non‐Hodgkin lymphoma (NHL) was 10%. 1 In the 1960s, it was 20%, 2, 3 and in the 1970s it was approximately 70%. 4, 5 Survival currently is reported to be 90%. 6 These jumps in cure rates reflect the experience acquired worldwide with regard to a complex group of diseases that require a complex group of therapies.
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Survival rates continue to improve with newer and improved treatment modalities. Despite the aggressive nature of acute lymphoblastic lymphoma, overall survival statistics offered by the National Cancer Institute among all ages is over 66%, and for children under the age of 5, the overall survival rate is almost 91%.

The 1-year and 5-year survival rates were 53.3% and 36.7%, respectively. Treatment approaches in T-LBL changed from conventional non-Hodgkin lymphoma (NHL) protocols to intensive NHL protocols but recently to ALL-designed protocols. T-ALL remission rates are 90%, and overall survival (OS) has improved to 60%-70%. Treatment of LBL with regimens typically used for non-Hodgkin lymphoma is associated with poor outcomes with only 58% complete remission (CR) rate and a 5-year diseasefree survival (DFS) rate of INTRODUCTION.
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95 Although the majority of lymphoblastic leukemias are of B lineage, only approximately 20% of lymphoblastic lymphomas express B-cell markers. 96,97 Practically all cases of lymphoblastic leukemia/lymphoma produce an enzyme, terminal The overall 5-year relative survival rate for all people with a non-Hodgkin lymphoma diagnosis is 71 percent. Relative survival rates compare people with this disease to those without it, and they The Stanford/NCOG regimen is an effective initial choice of therapy for lymphoblastic lymphoma patients, and is superior to the hyper-CVAD regimen in complete response rate and overall survival rate (p = 0.36). or lymphoblastic lymphoma To the Editor: (95% CI, 5-10 months), and the 2-year OS rate was 23% [Figure 1A]. Survival was similar in patients treated in S1 or S2 2011-09-01 · High survival rate with the LMT-89 regimen in lymphoblastic lymphoma (LL), but not in T-cell acute lymphoblastic leukemia (T-ALL) Leukemia , 20 ( 2006 ) , pp. 814 - 819 CrossRef View Record in Scopus Google Scholar Event-free survival at 24 months (EFS24) appears to be a strong surrogate endpoint in T cell lymphoblastic lymphoma (T-LBL), according to research published in the Annals of Hematology.